The medicinal composite film, as the name implies, is a film composed of various plastics, paper, and metal through an adhesive, and the thickness is generally less than 250um .
Common structures of common medicinal composite films are PET / PE, PET / PA / PE, PET / AL / PE, PET / VMPET / PE, VMPET / CPP , PT / AL / PE, PAPER / AL / PE , which are often used for stability Better medicine.
The common structure of the retort-resistant composite film is PET / AL / CPP, and the common structure of the puncture-resistant composite film is PET / PA / AL / PE , which is often used in products that require high-temperature cooking and vacuum packaging.
The common structure of the composite film with special barrier function is PET-Si / PE, PVA / PE, or PET / AL thickened / PE composite film, which is often used to block water, oxygen, light, or both oxygen, water and light. Products are generally aimed at products with more sensitive contents.
Common quality problems of medicinal composite membrane
1 Solvent residue
Solvent residue is the most common quality problem of composite membranes. Solvent residue can be directly migrated into medicines, affecting the safety of medication. It is recommended that pharmaceutical companies come to inspect each batch of materials, and can also choose products produced by solvent-free composite technology.
2 Peel strength
The unqualified peel strength is caused by the instability of the compounding and curing process of the packaging material during the production process. It represents a key indicator of the packaging plant's production process experience and level. The problem.
3 compatibility issues
The main source of the migration of the composite film to the drug in the drug is the plastic additive in the heat seal layer, or the component of the adhesive, or the ink that is back adhered to the inner layer.
4 Barrier performance
The barrier properties of the material include water vapor transmission rate and oxygen transmission rate. The above indicators directly affect the protection function of drugs and determine the validity period of drugs. The main reason for the above problems is that the packaging material factory has chosen unstable base materials.
It is recommended that the pharmaceutical factory inspect each batch and monitor the supplier's base material varieties, and it is not appropriate to compress procurement costs too low.
5 Friction coefficient
The above problems mainly come from the friction coefficient of the inner substrate, which directly affects the smooth running of the composite film in the packaging machine of the pharmaceutical factory.
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